Endocrine Abstracts

Introduction: Interferon treatment for hepatitis C has been associated with Graves’-like thyroiditis, developing in rare instances severe ophthalmopathy. The usual management is interferon withdrawal and high-dose corticosteroids, but it may interfere with the resolution of hepatitis. Hereby we report a case successfully treated with radiotherapy, which in our knowledge has never been previously reported.Case report: A 52-year-old woman was diagnose...

Objectives: aGLP1 have been positioned as an effective and safe treatment in patients with Type 2 Diabetes Mellitus (DM2). The objective was to evaluate the changes metabolic and body composition at 6 months after initiation with Semaglutide weekly subcutaneous added to its basic treatment in patients with DM2.Material and Methods: Prospective observational study. Treatment was started in 42 patients with DM2, with weekly subcutaneous Semaglutide with a ...

Objective: To investigate the effect of two hormone therapy (HT) regimens differing only in their progestin component on serum markers of apoptosis.Design: Randomized, double-blinded study.Patients: One hundred healthy postmenopausal women.Interventions: Patients were randomized to 17β-estradiol 1 mg/drosperinone 2 mg (E2/DSP) or 17β-estradiol 1 mg/norethisterone acetate 0.5 mg (E2</...

FAP is a dominant autosomic syndrome, due to mutation of the APC oncosuppressor gene, characterised by adenomatous polyps at the colon–rectal level, that progres to malignant degeneration. FAP extraintestinal manifestations include, although rare, the thyroid nodules and tumours. Neck ultrasound (US) is routinely useful to identify thyroid nodules, but the characterisation of their nature requires the cytology by a FNAb. The exact incidence of the thyroid tumours on FAP s...

Cushing’s disease is a debilitating endocrinopathy characterized by excessive cortisol levels in the blood which may be produced from tumours of the pituitary gland. The only way to achieve long term cure of Cushing’s disease is by Transphenoidal removal of the adenoma. ketoconazole, inhibit steroid (cortisol) production in the adrenal glands.The use of glucocorticids treatment before and after hypophisectomy is a classic management in the peri...

Introduction: Patients with severe cerebral Trauma are a risk population for developing hipopituytarism. Diagnosis of GHD need to study pituitary gland reserve with a stimulation test. Insulin Tolerance test (ITT) is the best standard test, although has important contraindication in these patients and its realization is not always a possible. We evaluate the diagnostic capacity of two alternative test (Glucagon Test an GHRH-GHRP6 test) and compared them with ITT.<p class="...

Objective: Evaluate the prevalence of adrenal insufficiency (AI) in Southern Province of Seville that comprises around 400.000 people.Materials and methods: Retrospective descriptive study that includes patients diagnosed with primary (PAI) and secondary (SAI) adrenal insufficiency that are followed up at Virgen de Valme University Hospital.Results: Out of the 125 patients with AI, 51 patients (40,8%) had PAI and 74 patients had SA...

Introduction: Over the last few years, there are some studies that suggests a close connection between Nonalcoholic Liver Disease (NAFLD) and increased cardiovascular (CV) risk in population with obesity. Indeed, these two conditions share common drivers, most notably insulin resistance and other elements of the metabolic syndrome. Notwithstanding the above, this affirmation does not have solid scientific evidence. The proliferation of Vasa Vasorum (VV) in the adventitial laye...

Introduction: The number of transgender men and women who seek gender-affirming therapy is rapidly increasing worldwide. It is still a population at high risk for several morbidities. The Basque Country Gender Identity Clinic was created in 2009 to centralize their medical care in the region.Aim: To determine the proportion of transgender individuals in the Basque Country, the prevalence of several morbidities in this transgender population, their evolut...

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...